Fug, I meant East.
The East Coast where the remains of the US military want to poison the only source of fresh clean water,
The Brotherhood of Dumb evolves into Enclave level fascists flying around in a murderblimp,
Mutants are downgraded from dumb but high functioning to 99% braindead savages,
Raiders are downgraded from actual factions to groups of themed enemy types,
Teams of scientists make androids just to fuck-with/replace people instead of doing something productive,
Rare and highly regulated pre-war power armor is just laying around all over the place so much so that raider gangs regularly have a set,
and Disney world somehow has power armor invented on the West coast after the apocalypse sealed in a pre-war vault.
I don't expect great lore or narrative from Beth-Fallout games.
But I would probably have fun with a big dumb third person action game like Fallout: Horizon Zero Dawn.
Since they said it was a spinoff and everything.